In this book on practical antibiotherapy in swine medicine, the author has tried to present, in a visual and practical way and with an updated view, the most important aspects a veterinary clinician should take into account to design appropriate antimicrobial treatments in swine herds. Thus, in this work, current pharmacological knowledge is reviewed with the help of real clinical cases solved by the author. Finally, it includes a comprehensive review of what a prudent use of these essential tools to ensure our animals’ health means.

This book has been prepared with all the veterinary professionals who dedicate themselves to clinical practice in mind, with the idea that it may be a useful reference tool. In addition, the author has structured the content in a way that will allow clinicians to reflect on the reasons for administering a particular drug treatment and to carry out a self-assessment of their work.

Author

Lorenzo José Fraile Sauce

Graduate in veterinary medicine and PhD in veterinary pharmacology from the University of Zaragoza (Spain). Professor of epidemiology and pharmacology at the University of Lleida (Spain). He also teaches students of the joint master’s degree in swine production and health offered by the Complutense University of Madrid, the University of Lleida and the University of Zaragoza.

Table of Contents

1. Introduction

     General concepts

     Pharmacokinetics (PK)

     Pharmacodinamics (PD)

     Utility of the PK-PD models. Design of the dosing regimen

     Classification of antimicrobials

     Practical aspects of dosing regimen

     Antimicrobial resistance

2. Treatment of respiratory diseases

     General concepts

     Acute respiratory diseases. Critical review of the application of antibiotics in the treatment

     Chronic respiratory diseases

3. Treatment of digestive diseases

     General concepts

     Treatment of acute diseases affecting the small intestine

     Treatment of chronic diseases affecting the distal part of the small intestine and the large intestine

4. Treatment of meningitis and skin infection

     General concepts

     Treatment of meningitis

     Treatment of skin infections

5. Treatment of mastitis-metritis-agalaxia syndrome in sows

     General concepts

     Treatment of MMA syndrome in sows

6. Prudent use of antimicrobials