The most updated information on avian influenza with a practical approach. The authors review the aetiology, clinical signs, diagnosis, and control of avian influenza viruses. It also includes numerous graphic resources to make the contents more understandable to readers

Author:

HELENA LAGE FERREIRA

Assistant Professor at University of São Paulo Brazil State University (UNESP, Brazil).

TAIANA PEREIRA DA COSTA

Postdoctoral fellowship on Avian Virology and Pathology (Autonomous University of Barcelona, Spain).

CINTIA HIROMI OKINO

Currently working at the Avian Virology Laboratory, Embrapa Swine and Poultry, a Brazilian Agricultural Research Corporation.

SHAMUS PATRICK KEELER

Postdoctoral research scholar at Washington University School of Medicine in St. Louis (MO, USA).

MUHAMMAD MUNIR

Fellow on Avian Innate Immunity and Host Genetic Diversity at The Pirbright Institute, UK.

Key Features:

➜ This handbook provides the most updated information on avian influenza (AI).

➜ Written by renowned experts in the field of diseases affecting the poultry industry,

including avian influenza.

➜ Practical and visual approach presenting numerous graphic resources.

Table of Contents:

1. Introduction

History and reports of influenza viruses

Aetiology

Hosts

Notification to OIE

2. Classification of AIV

Viral taxonomy

AI subtypes

AI nomenclature

Species specific influenza A viruses

AIV pathotypes

Antigenic variation of strains-drift and shift

Additional AIV classifications

3. Avian immune responses

Innate immune responses

Adaptive immune response

Cell-mediated immunity (CMI)

Antibody-mediated immunity

Cytokine storm

Evasion of immune response by influenza viruses

4. Pathogenesis

Shedding

Transmission

Molecular pathogenesis

Receptor binding specificity

Host susceptibility

5. Clinical signs and pathology

6. Sampling and diagnosis

Specimen sampling

Diagnostic methods

Virus identification

Molecular methods

Assessment of pathogenicity

Immunohistochemistry (IHC) and

immunofluorescence (IFIC)

Serological methods

7. Prevention and control

Prevention and control of AI outbreaks

Education

Biosecurity

Diagnosis

Surveillance

Vaccination

Transfer of passive immunity in birds

Eradication of AI

8. References